Trifluoroacetic acid → (RS)-1-{2-[4-(4-Fluorophenyl)-1H-imidazol-2-ylmethyl]-piperazin-1-yl}-1-[5-(4-fluorophenyl)-2-methylthiazol-4-yl]-methanone

반응식

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([CH2:29][c:30]2[nH:31][cH:32][c:33](-[c:35]3[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]3)[n:34]2)[N:11]([C:14](=[O:15])[c:16]2[n:17][c:18]([CH3:28])[s:19][c:20]2-[c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48]>>[NH:8]1[CH2:9][CH:10]([CH2:29][c:30]2[nH:31][cH:32][c:33](-[c:35]3[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]3)[n:34]2)[N:11]([C:14](=[O:15])[c:16]2[n:17][c:18]([CH3:28])[s:19][c:20]2-[c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[CH2:12][CH2:13]1

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 178433035HCID 178433035, 화합물

생성물 1

HCID 178433009(RS)-1-{2-[4-(4-Fluorophenyl)-1H-imidazol-2-ylmethyl]-piperazin-1-yl}-1-[5-(4-fluorophenyl)-2-methylthiazol-4-yl]-methanone

출처 및 근거

ORD 기록: ord-fe6c008857ae421682e06c749f468451
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

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