Dichloromethane → 2-[3-fluoro-4-(trifluoromethyl)phenyl]-N-[6-methyl-2-[1-[methyl(prop-2-enyl)amino]propan-2-yl]-1-oxoisoquinolin-5-yl]acetamide

반응식

[CH2:48]([Cl:49])[Cl:50].[CH3:1][S:2]([O:3][CH2:6][CH:7]([CH3:8])[n:9]1[c:10](=[O:35])[c:11]2[cH:12][cH:13][c:14]([CH3:34])[c:15]([NH:19][C:20]([CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)=[O:33])[c:16]2[cH:17][cH:18]1)(=[O:4])=[O:5].[CH3:36][NH:37][CH2:38][CH:39]=[CH2:40].[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47]>>[CH2:6]([CH:7]([CH3:8])[n:9]1[c:10](=[O:35])[c:11]2[cH:12][cH:13][c:14]([CH3:34])[c:15]([NH:19][C:20]([CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)=[O:33])[c:16]2[cH:17][cH:18]1)[N:37]([CH3:36])[CH2:38][CH:39]=[CH2:40]