Acetonitrile → [(3RS,4SR)-4-(3-Chloro-phenyl)-pyrrolidin-3-yl]-(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amine

반응식

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([N:20]([CH3:21])[CH2:22][c:23]2[cH:24][c:25]([F:33])[c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]2)[CH:11]([c:13]2[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]2)[CH2:12]1.[CH3:43][C:44]#[N:45].[Cl:34][C:35]([O:36][CH2:37][C:38]([Cl:39])([Cl:40])[Cl:41])=[O:42]>>[NH:8]1[CH2:9][CH:10]([N:20]([CH3:21])[CH2:22][c:23]2[cH:24][c:25]([F:33])[c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]2)[CH:11]([c:13]2[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]2)[CH2:12]1