Dichloromethane → 1-butyl-N-[1-(3,5-difluorophenyl)-4-[(3-ethylphenyl)methylamino]-3-hydroxybutan-2-yl]-4-(1,3-oxazol-2-yl)indole-6-carboxamide

HRID 961678

반응식

HRID 961678 반응식
[CH2:1]([CH2:2][CH2:3][CH3:4])[n:5]1[cH:6][cH:7][c:8]2[c:9](-[c:17]3[o:18][cH:19][cH:20][n:21]3)[cH:10][c:11]([C:14](=[O:15])[OH:16])[cH:12][c:13]12.[CH2:46]([Cl:47])[Cl:48].[NH2:22][CH:23]([CH:24]([CH2:25][NH:26][CH2:27][c:28]1[cH:29][c:30]([CH2:34][CH3:35])[cH:31][cH:32][cH:33]1)[OH:36])[CH2:37][c:38]1[cH:39][c:40]([F:45])[cH:41][c:42]([F:44])[cH:43]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[n:5]1[cH:6][cH:7][c:8]2[c:9](-[c:17]3[o:18][cH:19][cH:20][n:21]3)[cH:10][c:11]([C:14](=[O:16])[NH:22][CH:23]([CH:24]([CH2:25][NH:26][CH2:27][c:28]3[cH:29][c:30]([CH2:34][CH3:35])[cH:31][cH:32][cH:33]3)[OH:36])[CH2:37][c:38]3[cH:39][c:40]([F:45])[cH:41][c:42]([F:44])[cH:43]3)[cH:12][c:13]12

참가 물질

4

반응물 3

HCID 6344DichloromethaneHCID 210851691-butyl-4-(1,3-oxazol-2-yl)-1H-indole-6-carboxylic acidHCID 218657313-Amino-4-(3,5-difluoro-phenyl)-1-(3-ethyl-benzylamino)-butan-2-ol

생성물 1

HCID 210851881-butyl-N-[1-(3,5-difluorophenyl)-4-[(3-ethylphenyl)methylamino]-3-hydroxybutan-2-yl]-4-(1,3-oxazol-2-yl)indole-6-carboxamide

출처 및 근거

ORD 기록
ord-a6fd3bc2e9be4759b4203334fd12cadc
출처 데이터셋
Validation data from https://doi.org/10.1039/C8SC04228D

연결된 노트

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