Dimethylformamide → 4-(6-Acetylamino-2-chloro-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester

HRID 961705

반응식

[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH2:21][CH2:22][CH:23]([NH2:26])[CH2:24][CH2:25]1.[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([NH:8][C:9]([CH3:10])=[O:11])[n:7]1.[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[Cl:1][c:2]1[n:3][c:4]([NH:26][CH:23]2[CH2:22][CH2:21][N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:25][CH2:24]2)[cH:5][c:6]([NH:8][C:9]([CH3:10])=[O:11])[n:7]1

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 12682914-Amino-1-Boc-piperidine

HCID 4713752N-(2,6-dichloropyrimidin-4-yl)acetamide

생성물 1

HCID 866185454-(6-Acetylamino-2-chloro-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-304748a8ab8c4e4680e2593e1395475b
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

연결된 노트

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