Chloroacetyl chloride → 4-chloroacetyl-9,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one

반응식

[CH3:1][c:2]1[s:3][cH:4][c:5]2[c:6]1[NH:7][c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[NH:10][C:11]2=[O:12].[Cl:17][CH2:18][C:19](=[O:20])[Cl:21].[O:22]1[CH2:23][CH2:24][O:25][CH2:26][CH2:27]1>>[CH3:1][c:2]1[s:3][cH:4][c:5]2[c:6]1[N:7]([C:19]([CH2:18][Cl:17])=[O:20])[c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[NH:10][C:11]2=[O:12]

참가 물질

반응물 3

HCID 6577Chloroacetyl chloride

HCID 312751,4-Dioxane

HCID 126587009,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one

생성물 1

HCID 198042184-chloroacetyl-9,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one

출처 및 근거

ORD 기록: ord-de050f89fd0e4deaad1bf499140698a3
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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