Acetic Acid → 2-(2-Amino-4-chloro-6-fluoro-3-hydroxyphenyl)-5-trifluoromethylpyridazin-3-one

반응식

[CH3:24][C:25](=[O:26])[OH:27].[Cl:1][c:2]1[c:3]([OH:23])[c:4]([N+:20]([O-:21])=[O:22])[c:5](-[n:9]2[n:10][cH:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1.[Fe:28]>>[Cl:1][c:2]1[c:3]([OH:23])[c:4]([NH2:20])[c:5](-[n:9]2[n:10][cH:11][c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1

참가 물질

반응물 3

HCID 176Acetic Acid

HCID 23925Iron

HCID 186156602-(4-Chloro-6-fluoro-3-hydroxy-2-nitrophenyl)-5-trifluoromethylpyridazin-3-one

생성물 1

HCID 185196212-(2-Amino-4-chloro-6-fluoro-3-hydroxyphenyl)-5-trifluoromethylpyridazin-3-one

출처 및 근거

ORD 기록: ord-19ebe5a03a4340b48583b1af6b589681
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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