Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl bromoacetate → Ethyl 2-(2-(trifluoromethyl)phenoxy)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl bromoacetate | HCID 7748 | — |
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 2-Trifluoromethylphenol | HCID 67958 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Ethyl 2-(2-(trifluoromethyl)phenoxy)acetate | HCID 11354946 | — |
반응 단계
A mixture of 2-trifluoromethylphenol (1.62 g) in anhydrous acetonitrile was treated with cesium carbonate (3.25 g) and ethyl bromoacetate (1.75 g) and the reaction mixture stirred at room temperature for 2 hours. The reaction mixture was diluted with water and ethyl acetate and the organic layer washed with water and dried with brine and over sodium sulfate. Evaporation of ethyl acetate gave the title compound as a colourless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091237B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-6d696bea668f4b758ccefed342a68beb |
| 출처 메모 | uspto-grants-2006_08 |