Methyl bromoacetate → 4-Phenyl-4-((1-(3,5-bis(trifluoromethyl)phenyl)-2-methoxycarbonylmethoxy ethoxy)methyl)piperidine Hydrochloride

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This was prepared in a similar manner as Example 2 using the compound of Example 1 (d) and methyl bromoacetate. 1H NMR (360 MHz, d6 -DMSO) δ7.98 (1H, s), 7.75 (2H, s), 7.41-7.24 (5H, m), 4.68 (1H, t, J=5 Hz), 4.11 (2H, s), 3.62 (3H, s), 3.69-3.30 (4H, m), 3.29-3.10 (2H, m), 2.78-2.60 (2H, m), 2.39-2.00 (4H, m). MS (Cl+) 520 (M+H)+.

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