N-(2-Bromo-5-methoxyphenyl)acetamide → 1-(4-Acetylamino-5-bromo-2-hydroxyphenyl)-5-bromopentan-1-one

HRID 963340

반응식

HRID 963340 반응식
Br[C:2](=[O:8])[CH2:3][CH2:4][CH2:5][CH2:6][Br:7].C(NC1C=C(OC)C=CC=1Cl)(=O)C.[C:22]([NH:25][C:26]1[CH:31]=[C:30]([O:32]C)[CH:29]=[CH:28][C:27]=1[Br:34])(=[O:24])[CH3:23]>>[C:22]([NH:25][C:26]1[C:27]([Br:34])=[CH:28][C:29]([C:2](=[O:8])[CH2:3][CH2:4][CH2:5][CH2:6][Br:7])=[C:30]([OH:32])[CH:31]=1)(=[O:24])[CH3:23]

참가 물질

4

반응물 3

HCID 14493071N-(2-Bromo-5-methoxyphenyl)acetamideHCID 19081918N-(2-Chloro-5-methoxyphenyl)acetamideHCID 19081948HCID 19081948, 화합물

생성물 1

HCID 190819521-(4-Acetylamino-5-bromo-2-hydroxyphenyl)-5-bromopentan-1-one

실험 절차

Proceeding as in Example 4, Step (a), but replacing 1,5-dichlcoro-pentan-1-one with 1,5-dibromopentan-1-one and N-acetyl-2-chloro-5-methoxyaniline with N-acetyl-2-bromo-5-methoxyaniline, gave 1-(4-acetylamino-5-bromo-2-hydroxyphenyl)-5-bromopentan-1-one.

출처 및 근거

ORD 기록
ord-3e7e9b89fbaa476383574603d2ecba56
출처 데이터셋
uspto-grants-1998_06
특허 번호
US05763458

연결된 노트

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