Phosgene → 2-(2-Chloro-6-nitrophenyl)ethoxycarbonyl chloride
반응식
[C:1]([Cl:4])(Cl)=[O:2].[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:7]=1[CH2:15][CH2:16][OH:17]>C1COCC1>[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:7]=1[CH2:15][CH2:16][O:17][C:1]([Cl:4])=[O:2]참가 물질
4
실험 절차
Phosgene was introduced in a solution of 2-(2-chloro-6-nitrophenyl)ethanol (31 g, 154 mmol) in THF (190 ml, dist. over CaH2) at room temperature under stirring. After 2.5 h the excess phosgene and the solvent were removed by distillation in a high vacuum. 2-(2-chloro-6-nitrophenyl)ethoxycarbonyl chloride (39.4 g, 97%) was obtained as a yellow oil.
후처리
- customthe solvent were removed by distillation in a high vacuum
출처 및 근거
- ORD 기록
- ord-5eea3744c2ce48369a72f21b65a68c3e
- 출처 데이터셋
- uspto-grants-1998_06
- 특허 번호
- US05763599
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