Hydrogen Peroxide → 4,4,5,8-Tetramethylthiochroman-6-carboxylic acid-1,1-dioxide

HRID 964376

반응식

HRID 964376 반응식
[CH3:1][C:2]1([CH3:17])[C:11]2[C:6](=[C:7]([CH3:16])[CH:8]=[C:9]([C:13]([OH:15])=[O:14])[C:10]=2[CH3:12])S[CH2:4][CH2:3]1.OO.[S:20]([O-:23])(O)=[O:21].[Na+]>C(O)(=O)C>[CH3:17][C:2]1([CH3:1])[C:11]2[C:6](=[C:7]([CH3:16])[CH:8]=[C:9]([C:13]([OH:15])=[O:14])[C:10]=2[CH3:12])[S:20](=[O:23])(=[O:21])[CH2:4][CH2:3]1

참가 물질

5

반응물 3

HCID 784Hydrogen PeroxideHCID 129936864,4,5,8-Tetramethylthiochroman-6-carboxylic acidHCID 23665763Sodium Bisulfite

생성물 1

HCID 158698044,4,5,8-Tetramethylthiochroman-6-carboxylic acid-1,1-dioxide수율 90%

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
80 °C

실험 절차

4 ml of acetic acid was added to 5 g (0.02 mol) of 4,4,5,8-tetramethylthiochroman-6-carboxylic acid, further, 6.9 g (0.06 mol) of a 30% hydrogen peroxide aqueous solution was added, and the mixture was heated at 80° C. for 2 hours. 50 ml of a 2% sodium hydrogensulfite aqueous solution was added to the reaction mixture, and a precipitated solid was recovered by filtration to give 5.1 g (yield 90%) of 4,4,5,8-tetramethylthiochroman-6-carboxylic acid-1,1-dioxide.

후처리

  1. filtrationa precipitated solid was recovered by filtration

출처 및 근거

ORD 기록
ord-3cd28d42c7574b9cb7edd4129d826478
출처 데이터셋
uspto-grants-1998_06
특허 번호
US05767289

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