2,8-Diacetylamino-1-tetralone → 2-Acetylaminomethyl-8-amino-5-chloro-1-tetralone

HRID 964659노트

반응식

HRID 964659 반응식
C([NH:4][C:5]1[CH:6]=[CH:7][C:8]([Cl:18])=[C:9]2[C:14]=1[C:13](=[O:15])[CH:12]([C:16]#[N:17])[CH2:11][CH2:10]2)(=O)C.[C:19](NC1CCC2C(=C(NC(=O)C)C=CC=2)C1=O)(=[O:21])[CH3:20]>>[C:19]([NH:17][CH2:16][CH:12]1[CH2:11][CH2:10][C:9]2[C:14](=[C:5]([NH2:4])[CH:6]=[CH:7][C:8]=2[Cl:18])[C:13]1=[O:15])(=[O:21])[CH3:20]

참가 물질

3

반응물 2

HCID 120472982,8-Diacetylamino-1-tetraloneHCID 224494878-Acetylamino-5-chloro-2-cyano-1-tetralone

생성물 1

HCID 224495222-Acetylaminomethyl-8-amino-5-chloro-1-tetralone

실험 절차

The procedure of Example 1-(4) was followed by using 1.20 gm of the compound prepared in (3) above, instead of 2,8-diacetylamino-1-tetralone. The reaction product was post-treated to obtain 1.20 gm of the title compound.

후처리

  1. additionThe reaction product was post-treated

출처 및 근거

ORD 기록
ord-b4f8f826a7674439bc3356004c6300fe
출처 데이터셋
uspto-grants-1998_06
특허 번호
US05770605

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