2-(2-Chloroethoxy)tetrahydro-2H-pyran → 3,3-Dimethyl-1-(2-hydroxyethyl)-5-methanesulfonyl-1,3-dihydro-2H-indol-2-one

반응식

[CH3:1][C:2]1([CH3:16])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([S:11]([CH3:14])(=[O:13])=[O:12])[CH:9]=2)[NH:4][C:3]1=[O:15].Cl[CH2:18][CH2:19][O:20]C1CCCCO1>>[CH3:1][C:2]1([CH3:16])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([S:11]([CH3:14])(=[O:13])=[O:12])[CH:9]=2)[N:4]([CH2:18][CH2:19][OH:20])[C:3]1=[O:15]

참가 물질

반응물 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyran

HCID 225957463,3-Dimethyl-5-(methylsulfonyl)indolin-2-one

생성물 1

HCID 190750193,3-Dimethyl-1-(2-hydroxyethyl)-5-methanesulfonyl-1,3-dihydro-2H-indol-2-one

실험 절차

Prepared from 3,3-dimethyl-5-methanesulfonyl-1,3-dihydro-2H-indol-2-one and 2-(2-chloroethoxy)tetrahydro-2H-pyran.

출처 및 근거

ORD 기록: ord-3b220d50689d4739ae2021db8fbf429a
출처 데이터셋: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05773448

반응 노트

불러오는 중…