Ethyl alpha-benzylacetoacetate → HCID 178433370, 화합물

HRID 965680

반응식

HRID 965680 반응식
[CH2:1]([CH:8]([C:14](=O)[CH3:15])[C:9](OCC)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)(O)O.[NH2:21][C:22]([NH2:24])=[NH:23]>C(O)C>[NH2:24][C:22]1[N:23]=[C:9]([OH:10])[C:8]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:14]([CH3:15])[N:21]=1

참가 물질

4

반응물 2

HCID 246929Ethyl alpha-benzylacetoacetateHCID 286947Carbonic acid-guanidine (1:1)

생성물 1

HCID 178433370HCID 178433370, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of ethyl 2-benzyl-3-oxobutanoate (6 g, 27.2 mmol), guanidine carbonate (2.94 g, 16.3 mmol) and ethanol (20 ml) was refluxed for 10 hours. After cooling, the precipitate was filtered and washed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%).

후처리

  1. temperaturewas refluxed for 10 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitate was filtered
  4. washwashed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%)

출처 및 근거

ORD 기록
ord-f19885d0bc5e4cc6916e9d57a48c49c4
출처 데이터셋
uspto-grants-2005_10
특허 번호
US06951866B2

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