N-Methylisopropylamine → {2-{[Isopropyl(methyl)amino]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

HRID 9662

반응식

HRID 9662 반응식
Br[CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[C:8]([O:10]C)=O.[CH3:22][NH:23][CH:24]([CH3:26])[CH3:25]>>[CH:24]([N:23]([CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[CH2:8][OH:10])[CH3:22])([CH3:26])[CH3:25]

참가 물질

3

반응물 2

HCID 78485N-MethylisopropylamineHCID 21986318Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate

생성물 1

HCID 21986358{2-{[Isopropyl(methyl)amino]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

실험 절차

Prepared using intermediate 44 and N-methylisopropylamine. This compound was used directly without collection of analytical data for the preparation of Example 75.

후처리

  1. customPrepared
  2. customThis compound was used directly without collection of analytical data for the preparation of Example 75

출처 및 근거

ORD 기록
ord-0859d51250d044c38378d9f0c267c973
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091237B2

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