4-Oxo-1-phenylcyclohexane-1-carboxylic acid → 4-Oxo-1-phenyl-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide

HRID 966984

반응식

HRID 966984 반응식
[O:1]=[C:2]1[CH2:7][CH2:6][C:5]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)([C:8]([OH:10])=O)[CH2:4][CH2:3]1.[F:17][C:18]([F:32])([F:31])[C:19]1[CH:20]=[C:21]([CH:24]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:26]=1)[CH2:22][NH2:23]>>[O:1]=[C:2]1[CH2:3][CH2:4][C:5]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)([C:8]([NH:23][CH2:22][C:21]2[CH:24]=[C:25]([C:27]([F:28])([F:29])[F:30])[CH:26]=[C:19]([C:18]([F:17])([F:31])[F:32])[CH:20]=2)=[O:10])[CH2:6][CH2:7]1

참가 물질

3

반응물 2

HCID 3438864-Oxo-1-phenylcyclohexane-1-carboxylic acidHCID 5210993,5-Bis(trifluoromethyl)benzylamine

생성물 1

HCID 222935764-Oxo-1-phenyl-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide

실험 절차

Prepared from 4-oxo-1-phenylcyclohexanecarboxylic acid (Description 2) and 3,5-bis(trifluoromethyl)benzylamine according to the method of Example 177. m/z (ES+) 444 (M+1).

출처 및 근거

ORD 기록
ord-7fa656b71477492699a9f1d1e2c17860
출처 데이터셋
uspto-grants-2005_10
특허 번호
US06953792B2

연결된 노트

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