2-Chlorobenzenesulfonamide → 2-chloro-N-{[(2-{4-[2-ethyl-4-(4-fluorophenyl)-1H-imidazol-1-yl]phenyl}ethyl)amino]carbonyl}benzenesulfonamide

참여 물질

반응 단계

The title compound was prepared according to the procedure described in step 2 of Example 18 from phenyl 2-{4-[2-ethyl-4-(4-fluorophenyl)-1H-imidazol-1-yl]phenyl}ethylcarbamate and 2-chlorobenzenesulfonamide. MS (ESI) m/z 527 [M+H]+, 525 [M−H]−, 1H-NMR (CDCl3)δ1.25 (3H, t, J=7.5 Hz), 2.71 (2H, q, J=7.5 Hz), 2.85 (2H, t, J=7.0 Hz), 3.47-3.54 (2H, m), 6.57 (1H, br), 7.07 (2H, t, J=8.8 Hz), 7.19 (1H, s), 7.26 (2H, s), 7.40-7.46 (1H, m), 7.57-7.61 (2H, m), 7.73-7.78 (2H, m), 8.00 (2H, d, J=7.5 Hz).

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