Bromopinacolone → tert-butyl 2-[4-(4-tert-butyl-2-ethyl-1H-imidazol-1-yl)phenyl]ethylcarbamate

HRID 967851노트

반응식

HRID 967851 반응식
[C:1]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][C:15](=[O:21])[O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[CH:8][CH:7]=1)(=[NH:4])[CH2:2][CH3:3].Br[CH2:23][C:24](=O)[C:25]([CH3:28])([CH3:27])[CH3:26]>>[C:25]([C:24]1[N:4]=[C:1]([CH2:2][CH3:3])[N:5]([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][C:15](=[O:21])[O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[CH:8][CH:7]=2)[CH:23]=1)([CH3:28])([CH3:27])[CH3:26]

참가 물질

3

반응물 2

HCID 21642BromopinacoloneHCID 178458051HCID 178458051, 화합물

생성물 1

HCID 22291422tert-butyl 2-[4-(4-tert-butyl-2-ethyl-1H-imidazol-1-yl)phenyl]ethylcarbamate

실험 절차

The title compound was prepared according to the procedure described in step 4 of Example 26 from tert-butyl 2-[4-(propanimidoylamino)phenyl]ethylcarbamate and 1-bromo-3,3-dimethylbutan-2-one: MS (ESI) m/z 372 [M+H]+.

출처 및 근거

ORD 기록
ord-9eddf6dbc83f497ea9d7161894b9ea44
출처 데이터셋
uspto-grants-2005_10
특허 번호
US06956050B2

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