Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol → 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol | HCID 21986431 | — |
| 반응물 | 3-Methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde | HCID 21986550 | — |
| 반응물 | HCID 178418573 | HCID 178418573 | — |
| 생성물 | 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol | HCID 21986359 | — |
반응 단계
The title compound was prepared using a method analogous to that used for the preparation of 1-{5-[4-(trifluoromethyl)phenyl]thien-3-yl}ethanol (intermediate 126) using 3-methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde (intermediate 74) and methyl magnesium bromide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091237B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-11e7000f7bdf4162a75e44daa17cdd60 |
| 출처 메모 | uspto-grants-2006_08 |