Chloroacetyl chloride → 6,8-Dichloro-7-methyl-4H-benzo[1,4]oxazin-3-one

HRID 969306노트

반응식

HRID 969306 반응식
[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([Cl:9])[C:5]([CH3:10])=[C:4]([Cl:11])[CH:3]=1.Cl[CH2:13][C:14](Cl)=[O:15].C([O-])([O-])=O.[K+].[K+]>>[Cl:11][C:4]1[C:5]([CH3:10])=[C:6]([Cl:9])[C:7]2[O:8][CH2:13][C:14](=[O:15])[NH:1][C:2]=2[CH:3]=1

참가 물질

4

반응물 3

HCID 6577Chloroacetyl chlorideHCID 11430Potassium CarbonateHCID 1702242-Amino-4,6-dichloro-5-methylphenol

생성물 1

HCID 689121896,8-Dichloro-7-methyl-4H-benzo[1,4]oxazin-3-one

실험 절차

6-Amino-2.4 dichloro-3-metylphenol (1.9 g, 10 mmol), 2-chloroacetyl chloride (1.2 g, 11 mmol) and K2CO3 (3.0 g, 22 mmol) were mixed according to GP1 to give the title compound as a crude (80MF2225) (2.33 g).

출처 및 근거

ORD 기록
ord-0617c7bc41cd4ef587723172b7f75dcb
출처 데이터셋
uspto-grants-2007_12
특허 번호
US07307075B2

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