{2-Ethyl-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid → {2-Bromo-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid

HRID 9694

반응식

HRID 9694 반응식
C(OC(=O)COC1C=CC(S([Br:16])(=O)=O)=CC=1Cl)C.C([C:21]1[CH:31]=[C:30]([S:32][CH2:33][C:34]2[CH:38]=[C:37]([C:39]3[CH:44]=[CH:43][C:42]([C:45]([F:48])([F:47])[F:46])=[CH:41][CH:40]=3)[O:36][C:35]=2[CH3:49])[CH:29]=[CH:28][C:22]=1[O:23][CH2:24][C:25]([OH:27])=[O:26])C>>[Br:16][C:21]1[CH:31]=[C:30]([S:32][CH2:33][C:34]2[CH:38]=[C:37]([C:39]3[CH:44]=[CH:43][C:42]([C:45]([F:46])([F:48])[F:47])=[CH:41][CH:40]=3)[O:36][C:35]=2[CH3:49])[CH:29]=[CH:28][C:22]=1[O:23][CH2:24][C:25]([OH:27])=[O:26]

참가 물질

3

반응물 2

HCID 10225846{2-Ethyl-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acidHCID 21986401Ethyl[4-(bromosulfonyl)-2-chlorophenoxy]acetate2회

생성물 1

HCID 21986415{2-Bromo-4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid

실험 절차

The title compound was prepared from ethyl[4-(bromosulfonyl)-2-chlorophenoxy]acetate (intermediate 114) by a method analogous to that used for the preparation of {2-ethyl4-[({2-methyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetic acid (example 145).

출처 및 근거

ORD 기록
ord-7a45ae9fe9034a5182d6f166a7d872ad
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091237B2

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