Ethyl (4-mercapto-2-methylphenoxy)acetate → Ethyl{2-methyl-4-[({3-methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methyl)thio]phenoxy}acetate

반응식

C(OC(=O)COC1C=CC(SCC2C=C(C3C=CC(C(F)(F)F)=CC=3)OC=2)=CC=1C)C.[CH2:32]([O:34][C:35](=[O:46])[CH2:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([SH:44])=[CH:40][C:39]=1[CH3:45])[CH3:33].[CH3:47][C:48]1[CH:52]=[C:51]([C:53]2[CH:58]=[CH:57][C:56]([O:59][C:60]([F:63])([F:62])[F:61])=[CH:55][CH:54]=2)[S:50][C:49]=1[CH2:64]O>>[CH2:32]([O:34][C:35](=[O:46])[CH2:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([S:44][CH2:64][C:49]2[S:50][C:51]([C:53]3[CH:54]=[CH:55][C:56]([O:59][C:60]([F:62])([F:63])[F:61])=[CH:57][CH:58]=3)=[CH:52][C:48]=2[CH3:47])=[CH:40][C:39]=1[CH3:45])[CH3:33]

참가 물질

반응물 3

HCID 16641178Ethyl (4-mercapto-2-methylphenoxy)acetate2회

HCID 21986356{3-Methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol2회

HCID 21986477Ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate

생성물 1

HCID 21986465Ethyl{2-methyl-4-[({3-methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methyl)thio]phenoxy}acetate

실험 절차

The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl(4-mercapto-2-methylphenoxy)acetate (intermediate 4) and {3-methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol (intermediate 118).