Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl formate → Diethyl (5-formylfuran-2-yl)phosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl formate | HCID 7865 | — |
| 반응물 | Lithium diisopropylamide | HCID 2724682 | — |
| 반응물 | Phosphonic acid, 2-furanyl-, diethyl ester | HCID 12485182 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Diethyl (5-formylfuran-2-yl)phosphonate | HCID 46784019 | — |
반응 단계
solution of diethyl 2-furanphosphonate (1 mmole) in THF was treated with LDA (1.12 mmole, lithium N,N-diisopropylamide) at −78° C. for 20 min. Methyl formate (1.5 mmole) was added and the reaction was stirred for 1 h. Extraction and chromatography gave compound 1 as a clear yellow oil. Preferably this aldehyde can be prepared from 2-furaldehyde as described below.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07312219B2 |
| 출처 데이터셋 | uspto-grants-2007_12 |
| ORD ID | ord-b587e750aa334979877617a0b464899e |
| 출처 메모 | uspto-grants-2007_12 |