Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl formate → 2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl formate | HCID 7865 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 4-Methyltestosterone | HCID 236536 | — |
| 반응물 | 4,17alpha-Dimethyl-2-hydroxymethylene Testosterone | HCID 57349609 | — |
| 생성물 | 2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-one | HCID 70603288 | — |
반응 단계
2-Hydroxymethylene-17β-hydroxy-4-methylandrost-4-en-3-one was prepared from 32.28 g. of 17β-hydroxy-4-methylandrost-4-en-3-one and 32 ml. of methyl formate by a procedure analogous to that of Example 1, part (c) except that sodium hydride (15 g., 50%) was used in place of sodium methoxide. The 20 g. of product obtained was used directly in the next reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04160027 |
| 출처 데이터셋 | uspto-grants-1979_07 |
| ORD ID | ord-8c4c7750dc934c27b5fb5795da79a057 |
| 출처 메모 | uspto-grants-1979_07 |