Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-((Phenylmethoxy)carbonyl)glycine 4-nitrophenyl ester → HCID 131709998, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-((Phenylmethoxy)carbonyl)glycine 4-nitrophenyl ester | HCID 15616 | — |
| 반응물 | tert-Butyl L-alanyl-L-prolinate | HCID 12939800 | — |
| 반응물 | Chloroform methanol | HCID 21584188 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | HCID 131709998 | HCID 131709998 | — |
반응 단계
1.65 g of Z-Gly-ONP and 1.09 g of H-Ala-Pro-OtBu in 20 ml of ethyl acetate are allowed to stand for one hour at 0° C. and 20 hours at room temperature. The mix is then diluted with ethyl acetate, washed with 50% saturated potassium carbonate solution and with water, dried over sodium sulphate and evaporated. 2.06 g of an oil which is homogeneous according to thin layer chromatography result. Rf = 0.8 in the system chloroform-methanol (1:1) on silica gel.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04159981 |
| 출처 데이터셋 | uspto-grants-1979_07 |
| ORD ID | ord-14775f8a1a9f48ada785abe31afbeddb |
| 출처 메모 | uspto-grants-1979_07 |