Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Flutamide → N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Flutamide | HCID 3397 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide | HCID 16776651 | — |
반응 단계
Hydrogenate, at approximately 3 atmospheres, a mixture of 8.3 g. of 4'-nitro-3'-trifluoromethylisobutyranilide in 100 ml. of ethanol containing 0.5 g. of 5% palladium on charcoal. Filter and remove the solvent, obtaining 4'-amino-3'-trifluoromethylisobutyranilide, m.p. 114.5°-116° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04161540 |
| 출처 데이터셋 | uspto-grants-1979_07 |
| ORD ID | ord-ad37a73163f6419ba8063be514ea3e3c |
| 출처 메모 | uspto-grants-1979_07 |