4-Bromo-2-fluoroaniline → 1-(4-amino-3-fluoro-phenyl)-4-benzyloxy-1H-pyridin-2-one

반응식

[Br:16][c:17]1[cH:18][c:19]([F:24])[c:20]([NH2:21])[cH:22][cH:23]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[nH:12][cH:13][cH:14]1.[NH2:25][c:26]1[cH:27][cH:28][c:29](-[n:30]2[cH:31][cH:32][cH:33][cH:34][c:35]2=[O:36])[cH:37][c:38]1[F:39]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[n:12](-[c:17]2[cH:18][c:19]([F:24])[c:20]([NH2:21])[cH:22][cH:23]2)[cH:13][cH:14]1

참가 물질

반응물 3

HCID 1230504-Bromo-2-fluoroaniline

HCID 36077244-Benzyloxy-2(1H)-pyridone

HCID 221815481-(4-Amino-3-fluorophenyl)pyridin-2-one

생성물 1

HCID 668824131-(4-amino-3-fluoro-phenyl)-4-benzyloxy-1H-pyridin-2-one

출처 및 근거

ORD 기록: ord-5a6fe96aab5042afa30841a32f3e383c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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