Ethanol → Benzene, 1,3-dichloro-5-nitro-

HRID 972667

반응식

HRID 972667 반응식
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:5](N)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.C(O)C.S(=O)(=O)(O)O.N([O-])=O.[Na+]>O>[Cl:1][C:2]1[CH:3]=[C:4]([N+:10]([O-:12])=[O:11])[CH:5]=[C:7]([Cl:9])[CH:8]=1

참가 물질

6

반응물 4

HCID 702EthanolHCID 1118Sulfuric AcidHCID 758932,4-Dichloro-6-nitroanilineHCID 23668193Sodium Nitrite

생성물 1

HCID 12064Benzene, 1,3-dichloro-5-nitro-수율 95%

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

207 parts of 4,6-dichloro-2-nitro-aniline are introduced into 400 parts of ethanol and 900 parts of water, and 400 parts of concentrated sulfuric acid (98 percent strength by weight) are then added to the mixture. A solution of 105 parts of NaNO2 in 175 parts of water is run in at 80° C., as described in Example 1. The mixture is cooled and the product is filtered off. 182 parts (95% of theory) of 3,5-dichloro-nitro-benzene, of melting point 56°-59° C., are obtained.

후처리

  1. additionare then added to the mixture
  2. customis run in at 80° C.
  3. temperatureThe mixture is cooled
  4. filtrationthe product is filtered off

출처 및 근거

ORD 기록
ord-c9bf08f38efb46f0987d460193911431
출처 데이터셋
uspto-grants-1977_10
특허 번호
US04053527

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