Dimethylformamide → 4-Cyano-2-(3-cyanophenyl)-pyridine

반응식

Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10](Br)[CH:9]=2)[CH:3]=1.[Cu](C#N)[C:16]#[N:17].[CH3:20][N:21](C)C=O>>[C:16]([C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:20]#[N:21])[CH:9]=2)[CH:3]=1)#[N:17]

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 199886504-Chloro-2-(3-bromophenyl)-pyridine

HCID 178418260HCID 178418260, 화합물

생성물 1

HCID 199886564-Cyano-2-(3-cyanophenyl)-pyridine

실험 절차

Starting from 4-chloro-2-(3-bromophenyl)-pyridine, the title compound is prepared by reaction with copper cyanide in boiling N,N-dimethylformamide.

출처 및 근거

ORD 기록: ord-58500937992f497fbdcd8217a91d8ebb
출처 데이터셋: uspto-grants-1991_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05064832

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