Hydrogen Cyanide → 2-Hydroxy-4-phenylbutanenitrile

HRID 974107노트

반응식

HRID 974107 반응식
[C:1]1([CH2:7][CH2:8][CH:9]=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O-])(=O)C.[Na+].[CH:16]#[N:17]>>[OH:10][CH:9]([CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[C:16]#[N:17]

참가 물질

4

반응물 3

HCID 768Hydrogen CyanideHCID 7707BenzenepropanalHCID 517045Sodium Acetate

생성물 1

HCID 109098692-Hydroxy-4-phenylbutanenitrile

실험 절차

In a 300 ml flask, 134 g of 3-phenylpropanal and 1.4 g of 10% aqueous sodium acetate solution were placed, to which 27 g of hydrocyanic acid was added in dropwise maintaining the reaction temperature at 20° to 25° C., thereafter the reaction mixture was kept standing for 30 min.

후처리

  1. additionwas added
  2. temperaturein dropwise maintaining the reaction temperature at 20° to 25° C.

출처 및 근거

ORD 기록
ord-195888bdc1f94ab2a580c2a60e8b69d5
출처 데이터셋
uspto-grants-1991_11
특허 번호
US05066826

반응 노트

불러오는 중…