Chloroacetonitrile → 2-(4-Benzylpiperidin-1-yl)acetonitrile
반응식
[CH2:1]([N:3](CC)CC)[CH3:2].ClCC#N.[CH2:12]([CH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1(C)C=CC=CC=1>[CH2:12]([CH:19]1[CH2:24][CH2:23][N:22]([CH2:2][C:1]#[N:3])[CH2:21][CH2:20]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1참가 물질
5
실험 절차
40.8 ml of triethylamine and 22.2 g of chloroacetonitrile are dissolved in 180 ml of toluene, and 51.6 g of 4-benzylpiperidine are then added dropwise all at once.
출처 및 근거
- ORD 기록
- ord-395d55e3a4ac4cca974c1bb33955e569
- 출처 데이터셋
- uspto-grants-1991_11
- 특허 번호
- US05068064
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