Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Dimethoxytetrahydrofuran → 1-[3-(2,4-Difluorophenyl)propyl]-1H-pyrrole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Dimethoxytetrahydrofuran | HCID 19986368 | — |
| 반응물 | HCID 22669139 | HCID 22669139 | — |
| 생성물 | 1-[3-(2,4-Difluorophenyl)propyl]-1H-pyrrole | HCID 19986371 | — |
반응 단계
17.1 g (0.10 mol) of 3-(2,4-difluorophenyl)propylamine are heated at 260° C. for 2 hours in an autoclave with 13.2 g (0.10 mol) of 2,4-dimethoxytetrahydrofuran. The reaction mixture is cooled and then purified by vacuum distillation. 10.6 g (48% of theory) of a colourless oil which boils at 80° C. and 0.2 mbar or 146°-147° C. and 15 mbar are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05068371 |
| 출처 데이터셋 | uspto-grants-1991_11 |
| ORD ID | ord-54f1e1a3b3494f0d8649e77445d4fe39 |
| 출처 메모 | uspto-grants-1991_11 |