tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → (RS)-[2-(3-{3-[2-Methyl-6-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-phenyl}-3-oxo-propionylamino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:18])[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)=[O:19].[C:20]([CH3:22])([CH3:23])([O:24][C:25](=[O:21])[CH2:26][C:27](=[O:28])[c:29]1[cH:30][c:31](-[c:35]2[cH:36][c:37]([CH3:49])[n:38][c:39]([CH2:41][O:42][CH:43]3[O:44][CH2:45][CH2:46][CH2:47][CH2:48]3)[cH:40]2)[cH:32][cH:33][cH:34]1)[CH3:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:18][C:25](=[O:24])[CH2:26][C:27](=[O:28])[c:29]2[cH:30][c:31](-[c:35]3[cH:36][c:37]([CH3:49])[n:38][c:39]([CH2:41][O:42][CH:43]4[O:44][CH2:45][CH2:46][CH2:47][CH2:48]4)[cH:40]3)[cH:32][cH:33][cH:34]2)[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)=[O:19]