참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,2,4,5-Tetrachlorobenzene | HCID 7270 | — |
| 반응물 | Lithium Chloride | HCID 433294 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 촉매 | Bis(cyclopentadienyl)titanium(IV) chloride | HCID 416358 | — |
| 생성물 | 1,2,3-Trichlorobenzene | HCID 6895 | — |
반응 단계
A flask equipped with a magnetic stir bar and a water cooled condenser with an oil bubbler was charged with 1,2,4,5-tetrachlorobenzene (648 mg, 3.0 mmol), sodium tetrahydridoborate (1135 mg, 30.0 mmol), bis(η5 -cyclopentadienyl)titanium dichloride (75 mg, 0.3 mmol) and 1-methyl-2pyrrolidine (NMP; 30.0 ml). The reaction mixture was heated at 96° C. in an oil bath. After 4.25 hours, lithium chloride (1.09 g, 30.0 mmol) was added. Aliquots were withdrawn by syringe, quenched with water, and extracted with diethyl ether. The ether layer was analyzed with the results shown in the following table. Only trichlorobenzene was produced.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05608135 |
|---|
| 출처 데이터셋 | uspto-grants-1997_03 |
|---|
| ORD ID | ord-afb72519c4d7429caf96dfaa4c7ee144 |
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| 출처 메모 | uspto-grants-1997_03 |
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