1-(4-Bromophenyl)cyclobutanol → 8-(2-Chloro-benzenesulfonyl)-2-[4-(1-hydroxy-cyclobutyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one

반응식

[Br:22][c:23]1[cH:24][cH:25][c:26]([C:29]2([OH:33])[CH2:30][CH2:31][CH2:32]2)[cH:27][cH:28]1.[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][NH:17][C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:23]4[cH:24][cH:25][c:26]([C:29]5([OH:33])[CH2:30][CH2:31][CH2:32]5)[cH:27][cH:28]4)[C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1

참가 물질

반응물 2

HCID 120954191-(4-Bromophenyl)cyclobutanol

HCID 595779948-(2-Chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one

생성물 1

HCID 595779188-(2-Chloro-benzenesulfonyl)-2-[4-(1-hydroxy-cyclobutyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one

출처 및 근거

ORD 기록: ord-a4d7aa60060746f4afd87e1182e19969
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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