9-Azidononanoic acid → 9-Aminononanoic acid

HRID 975790

반응식

HRID 975790 반응식
[N:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[N+]=[N-]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13]

참가 물질

4

반응물 1

HCID 152305499-Azidononanoic acid

생성물 1

HCID 1368779-Aminononanoic acid

시약·촉매·용매 2

HCID 131709914Lindlars catalyst촉매HCID 702Ethanol용매

실험 절차

9-Azido-nonanoic acid (2.83 g, 14.2 mmol) was dissolved in ethanol (30 mL) and Lindlar catalyst (300 mg) added. The solution was hydrogenated at 50 psi, 30° C. for 4 hours, after which the catalyst was removed by filtration through Kieselguhr, washing with methanol. The solvent was removed in vacuo to give a pale yellow solid, 1.7 g (70%);

후처리

  1. customafter which the catalyst was removed by filtration through Kieselguhr
  2. washwashing with methanol
  3. customThe solvent was removed in vacuo
  4. customto give a pale yellow solid, 1.7 g (70%)

출처 및 근거

ORD 기록
ord-4be2edef1fd94a7181ae9cdef2e4679d
출처 데이터셋
uspto-grants-1997_03
특허 번호
US05610145

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