HCID 19968441, 화합물 → HCID 10220867, 화합물

HRID 975828노트

반응식

HRID 975828 반응식
S(O)(O)(=O)=O.[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:18]3([CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[NH:17][CH2:16][CH2:15][CH:14]=2)=[CH:9][CH:8]=1>O>[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:18]3([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[NH:17][CH2:16][CH2:15][CH:14]=2)=[CH:9][CH:8]=1

참가 물질

3

반응물 1

HCID 19968441HCID 19968441, 화합물

생성물 1

HCID 10220867HCID 10220867, 화합물

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

A mixture of 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene sulphate (0.5 g, prepared as described in Example 5) and water (5 ml) was stirred at ambient temperature to give, initially, a mobile suspension which rapidly thickened. Water (5 ml) was added to aid mobility and the solid was collected by filtration, washed with water (5 ml) and dried in vacuo at ambient temperature to give 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene 0.5 sulphate, 2.1 hydrate as a white solid. Yield 0.3 g, mp 205°-215° C.

후처리

  1. customto give
  2. filtrationthe solid was collected by filtration
  3. washwashed with water (5 ml)
  4. customdried in vacuo at ambient temperature

출처 및 근거

ORD 기록
ord-a5d880275bbe46b8bbafc0240e40e2b8
출처 데이터셋
uspto-grants-1997_03
특허 번호
US05610161

반응 노트

불러오는 중…