Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 6-[3-(4-(aminoiminomethyl)phenylamino)-3-oxopropyl]-3,4,5,6-tetrahydro-2H-pyran-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 6-[3-(4-cyanophenylamino)-3-oxopropyl]-3,4,5,6-tetrahydro-2H-pyran-2-one | HCID 19036627 | — |
| 반응물 | Acetonitrile ether | HCID 21885917 | — |
| 생성물 | 6-[3-(4-(aminoiminomethyl)phenylamino)-3-oxopropyl]-3,4,5,6-tetrahydro-2H-pyran-2-one | HCID 70077971 | — |
반응 단계
The title compound was prepared from the product of step B (770 mg, 2.83 mmol) in a manner similar to example 1, step G to give 430 mg (38%) of product as TFA salt after reverse phase chromatography and trituration with CH3CN/Et2O (m.p. 151°-153° C. dec.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05612355 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-5e3249e1962f4e75ad970cf575400a0c |
| 출처 메모 | uspto-grants-1997_03 |