Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Carbonate → Hydrochloric Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | Hydroxylamine HCl | HCID 21645 | — |
| 반응물 | 3-(4-Cyanophenyl)-2-oxo-5-oxazolidinecarboxylic acid | HCID 15340939 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | HCID 131719938 | HCID 131719938 | — |
반응 단계
27.9 g of 3-(4-cyanophenyl)-2-oxo-5-oxazolidine carboxylic acid [obtainable according to Example 1] and 26.4 g of hydroxylammonium chloride are boiled for 5 h in a mixture of 750 ml of methanol and 30 ml of water in the presence of 53.4 g of sodium carbonate. The precipitate formed is filtered off with suction, washed with methanol and dried. Treatment with hydrochloric acid gives 3-[4-(amino(hydroxylimino)methyl)phenyl]-2-oxo-5-oxazolidinecarboxylic acid, hydrochloride, m.p. 205°-208°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05614535 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-ebafdefec83f481baf0af317c189a8f8 |
| 출처 메모 | uspto-grants-1997_03 |