Tetrahydrofuran → N-[(4-{4-[(2-amino-6-phenylpyrimidin-4-yl)amino]phenoxy}pyridin-2-yl)methyl]4-fluorobenzamide

반응식

[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[F:30][c:31]1[cH:32][cH:33][c:34]([C:35](=[O:36])[Cl:37])[cH:38][cH:39]1.[NH2:1][CH2:2][c:3]1[n:4][cH:5][cH:6][c:7]([O:9][c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[n:18][c:19]([NH2:29])[n:20][c:21](-[c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[cH:22]3)[cH:14][cH:15]2)[cH:8]1>>[NH:1]([CH2:2][c:3]1[n:4][cH:5][cH:6][c:7]([O:9][c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[n:18][c:19]([NH2:29])[n:20][c:21](-[c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[cH:22]3)[cH:14][cH:15]2)[cH:8]1)[C:35]([c:34]1[cH:33][cH:32][c:31]([F:30])[cH:39][cH:38]1)=[O:36]

참가 물질

반응물 3

HCID 8028Tetrahydrofuran

HCID 678794-Fluorobenzoyl chloride

HCID 57833404HCID 57833404, 화합물

생성물 1

HCID 57833288N-[(4-{4-[(2-amino-6-phenylpyrimidin-4-yl)amino]phenoxy}pyridin-2-yl)methyl]4-fluorobenzamide

출처 및 근거

ORD 기록: ord-5698b90cb220455eb23f4e949cec3b0c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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