Tetrahydrofuran → 3-[hydroxy-(1-triisopropylsilanyl-1H-indol-5-yl)-methyl]-3-phenyl-pyrrolidine-1-carboxylic acid methyl ester

반응식

[Br:6][c:7]1[cH:8][c:9]2[cH:10][cH:11][n:12]([Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[c:13]2[cH:14][cH:15]1.[C:1]([Li:2])([CH3:3])([CH3:4])[CH3:5].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:26][O:27][C:28](=[O:29])[N:30]1[CH2:31][C:32]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)([CH:41]=[O:42])[CH2:33][CH2:34]1>>[c:7]1([CH:41]([C:32]2([c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[CH2:31][N:30]([C:28]([O:27][CH3:26])=[O:29])[CH2:34][CH2:33]2)[OH:42])[cH:8][c:9]2[cH:10][cH:11][n:12]([Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[c:13]2[cH:14][cH:15]1