Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Dichloroaniline → 3-(3,5-Dichlorophenyl)-5-methyl-4-thiazolidinone 1-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Dichloroaniline | HCID 12281 | — |
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 반응물 | 3-(3,5-Dichlorophenyl)-5-methyl-4-thiazolidinone | HCID 13853385 | — |
| 반응물 | Thiazolidinone | HCID 20553328 | — |
| 반응물 | HCID 178473673 | HCID 178473673 | — |
| 생성물 | 3-(3,5-Dichlorophenyl)-5-methyl-4-thiazolidinone 1-oxide | HCID 13853386 | — |
반응 단계
3,5-Dichloroaniline was converted to 3-(3,5-dichlorophenyl)-5-methyl-4-thiazolidinone in accordance with the procedure of Example 4. The only difference was that thiolactic acid was used instead of mercaptoacetic acid. The 3-(3,5-dichlorophenyl)-5-methyl-4-thiazolidinone had a melting point of 80°-88° C. This thiazolidinone (18 g) was oxidized with one equivalent of m-chloroperoxybenzoic acid (14 g) in the same manner as described in Example 2. After removal of the solvent, the reaction product was recrystallized from isopropyl alcohol to yield 3-(3,5-dichlorophenyl)-5-methyl-4-thiazolidinone 1-oxide, m.p. 146°-149° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04664694 |
| 출처 데이터셋 | uspto-grants-1987_05 |
| ORD ID | ord-76f70d012ff04b348964ca0546b61c5d |
| 출처 메모 | uspto-grants-1987_05 |