참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | 1,4-Dimethylpiperazine | HCID 7818 | — |
| 반응물 | 2-Bromoethyl thiolacetate | HCID 57091359 | — |
| 생성물 | 1-[2-(Acetylsulfanyl)ethyl]-1,4-dimethylpiperazin-1-ium bromide | HCID 20203366 | — |
반응 단계
A solution of 2-bromoethyl thiolacetate *(2.20 g, 0.012 mol) and 1,4-dimethylpiperazine (1.95 mL, 0.014 mol) in acetone (4 mL) was stirred at 50° C. for 65 h. After cooling to 25° C., the liquid phase was decanted from the gum which was triturated twice in diethyl ether; a hygroscopic yellowish powder, 3.2 g (90%) was obtained; ir (Nujol) νmax : 1685 (C=O of thioester) cm-1 ; 1Hmr (D2O) δ: ##STR141##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04665170 |
|---|
| 출처 데이터셋 | uspto-grants-1987_05 |
|---|
| ORD ID | ord-2dce7a7d2c4e4001a1c521cdb3e344ab |
|---|
| 출처 메모 | uspto-grants-1987_05 |
|---|
