HCID 86740397, 화합물 → HCID 86741500, 화합물

HRID 978851노트

반응식

HRID 978851 반응식
[C:1]([S:4][C@H:5]1[N:8]([S:9]([O-:12])(=[O:11])=[O:10])[C:7](=[O:13])[C@H:6]1[NH:14][C:15](=[O:30])[C:16]([C:20]1[N:21]=[C:22]([NH:25]C(=O)CCl)[S:23][CH:24]=1)=[N:17][O:18][CH3:19])(=[O:3])[CH3:2].[Na+:31].C(=S)(SC)N.[Na]>O>[C:1]([S:4][C@H:5]1[N:8]([S:9]([O-:12])(=[O:11])=[O:10])[C:7](=[O:13])[C@H:6]1[NH:14][C:15](=[O:30])[C:16]([C:20]1[N:21]=[C:22]([NH2:25])[S:23][CH:24]=1)=[N:17][O:18][CH3:19])(=[O:3])[CH3:2].[Na+:31]

참가 물질

4

반응물 2

HCID 86740397HCID 86740397, 화합물HCID 86740405HCID 86740405, 화합물

생성물 1

HCID 86741500HCID 86741500, 화합물수율 18.7%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of 0.10 g of sodium (3R,4R)-4-acetylthio-3-[2-(2-chloroacetamidothiazol-4-yl)-2-methoxyiminoacetamido]-2-oxoazetidine-1-sulfonate in 5 ml of water is added under ice-cooling 0.030 g of sodium monomethyl dithiocarbamate, and the mixture is stirred for 3 hours at room temperature. The same procedure as Example 3B yields 0.016 g of sodium (3R,4R)-4-acetylthio-3-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-2-oxoazetidine-1-sulfonate.

출처 및 근거

ORD 기록
ord-735a122bbaab4c69a481b6b4008a647e
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04665067

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