3-Methoxypropylamine → 2-chloro-5-methylamino-4-nitro-N-gamma-methoxypropylaniline

HRID 978920

반응식

HRID 978920 반응식
[Cl:1][C:2]1[C:9](Cl)=[CH:8][C:5]([NH:6][CH3:7])=[C:4]([N+:11]([O-:13])=[O:12])[CH:3]=1.[CH3:14][O:15][CH2:16][CH2:17][CH2:18][NH2:19]>>[Cl:1][C:2]1[CH:3]=[C:4]([N+:11]([O-:13])=[O:12])[C:5]([NH:6][CH3:7])=[CH:8][C:9]=1[NH:19][CH2:18][CH2:17][CH2:16][O:15][CH3:14]

참가 물질

3

반응물 2

HCID 16723-MethoxypropylamineHCID 2893174,5-Dichloro-n-methyl-2-nitroaniline

생성물 1

HCID 704266462-chloro-5-methylamino-4-nitro-N-gamma-methoxypropylaniline

실험 절차

0.059 mole (13 g) of 4,5-dichloro-2-nitro-N-methylaniline prepared in the previous stage is heated for 4 hours in 40 ml of 3-methoxypropylamine on a steam bath. After dilution with iced water and acidifying with concentrated hydrochloric acid, the expected product is filtered off. Recrystallized from 96° ethanol, it melts at 99° C.

후처리

  1. filtrationAfter dilution with iced water and acidifying with concentrated hydrochloric acid, the expected product is filtered off
  2. customRecrystallized from 96° ethanol, it melts at 99° C.

출처 및 근거

ORD 기록
ord-a1bced3aac7848849ba5ddfb4ac4b4cf
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04666453

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