1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 2-Benzyl-1-[4-(4-(4-(4-fluorophenyl)methylphenyl)piperazin-1-yl)butyrylamino]-6-methylbenzene

HRID 979

반응식

HRID 979 반응식
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:21])[CH2:17][CH2:18][CH2:19]Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]2[CH:35]=[CH:34][C:33]([N:36]3[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]3)=[CH:32][CH:31]=2)=[CH:25][CH:24]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:21])[CH2:17][CH2:18][CH2:19][N:39]1[CH2:38][CH2:37][N:36]([C:33]2[CH:32]=[CH:31][C:30]([CH2:29][C:26]3[CH:27]=[CH:28][C:23]([F:22])=[CH:24][CH:25]=3)=[CH:35][CH:34]=2)[CH2:41][CH2:40]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 15199981-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 196942282-Benzyl-1-(4-chlorobutyrylamino)-6-methylbenzene

생성물 1

HCID 196942462-Benzyl-1-[4-(4-(4-(4-fluorophenyl)methylphenyl)piperazin-1-yl)butyrylamino]-6-methylbenzene

실험 절차

The compound (14) synthesized in Reference Example 14 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

후처리

  1. customto produce the above compound in the same way as Example 1

출처 및 근거

ORD 기록
ord-0aee0a9e47044bef97598b5d38bfad3e
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723475

연결된 노트

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