Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Dithionite → 4-chloro-3-hydroxy-10H-phenothiazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Dithionite | HCID 24489 | — |
| 반응물 | 3H-Phenothiazin-3-one, 4-chloro- | HCID 11776748 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-chloro-3-hydroxy-10H-phenothiazine | HCID 9881418 | 95% |
반응 단계
A solution of Na2S2O4 (70 g) in water (500 ml) was added to a solution of 4-chloro-3H-phenothiazin-3-one (50 g) in DMF (1200 ml). The reaction mixture was stirred at room temperature for 3 hours and then poured in 5 liters of water. The resulting precipitate was then filtered to give the 4-chloro-3-hydroxy-10H-phenothiazine (95%). m.p.: 110° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04666907 |
| 출처 데이터셋 | uspto-grants-1987_05 |
| ORD ID | ord-59864131e5c34b0582e817f322c40d52 |
| 출처 메모 | uspto-grants-1987_05 |