HCID 21621270, 화합물 → HCID 87126116, 화합물

HRID 979263노트

반응식

HRID 979263 반응식
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][O:6][N:7]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.C[Si](C)(C)[O-].[K+:28]>C1(C)C=CC=CC=1>[K+:28].[CH2:15]([N:7]([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[O:6][CH2:5][CH2:4][C:3]([O-:22])=[O:2])[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

참가 물질

4

반응물 2

HCID 21621270HCID 21621270, 화합물HCID 23668039Potassium trimethylsilanolate

생성물 1

HCID 87126116HCID 87126116, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a stirred solution of 9.75 g of the compound of Example I in 100 ml of toluene is added 3.85 g of potassium trimethylsilanolate. After stirring the mixture at room temperature for 12 hours, the mixture is concentrated under reduced pressure and the residue is triturated with ether to leave the title compound as an off-white hygroscopic solid.

후처리

  1. concentrationthe mixture is concentrated under reduced pressure
  2. customthe residue is triturated with ether

출처 및 근거

ORD 기록
ord-e09a25c6a02a4ae192969210919bf411
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04666962

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