Water → HCID 20202084, 화합물

HRID 979303노트

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HRID 979303 반응식
[CH:1]1[C:14]2[C:5]([O:6][C:7]3[C:12]([N:13]=2)=[CH:11][CH:10]=[CH:9][CH:8]=3)=[CH:4][C:3](=[O:15])[CH:2]=1.[Cl:16]Cl.O>C(O)(=O)C>[Cl:16][C:4]1[C:3](=[O:15])[CH:2]=[CH:1][C:14]2[C:5]=1[O:6][C:7]1[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=1)[N:13]=2

참가 물질

5

반응물 3

HCID 962WaterHCID 24526ChlorineHCID 114834Phenoxazinone

생성물 1

HCID 20202084HCID 20202084, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

실험 절차

To a solution of 1.2 g of 3H-phenoxazin-3-one in acetic acid (25 ml) was added K2Cr2O7 (3.7 g). A solution of chlorine in acetic acid was added dropwise to the resulting suspension. After disappearance of the starting material, as monitored by TLC, the reaction mixture was poured into 200 ml of H2O and the resulting precipitate was filtered (1.2 g) and chromatographed on silica gel to yield the title compound.

후처리

  1. filtrationthe resulting precipitate was filtered (1.2 g)
  2. customchromatographed on silica gel

출처 및 근거

ORD 기록
ord-9cd040a5fb1546fea51a863e04a35a03
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04667032

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